FCS EXPRESS: Clinical tokens

FCS Express 4 Flow Cytometry IVD combines ease of use with many critical features that are needed by clinical flow laboratories. In response to customer feedback, the team at De Novo Software has added new tokens only available in this clinically focused version. The new tokens allow triggering of the following items based on the token value:

  • Classification
  • Changing font size, type, and color
  • View and hide pages
  • Batch Processing

Statistic Classifier Tokens

Statistic Classier tokens are not limited to the Clinical version of FCS Express 4, but they are certainly more widely used by labs doing clinical types of analysis than those doing research assays. This type of token can be used to automatically classify the staining intensity of individual CD Markers used to screen a leukemia/ lymphoma sample into standardized ranges such as Negative, Dim, Moderate or Bright based upon your hematopathologist's own criteria. They can automatically interpret the results of other tokens used in your layout such as interpreting your CD4/CD8 ratio token results as "normal" or "abnormal".

Font Formatting Tokens

Now you can control which font style and color is displayed by any token based upon that token's value or result. Flag out of control values in bright red text while displaying acceptable results in another color or font. Enhance or color-code your assay results to improve and facilitate validation and review.

A classifier token has been applied in the sample below to display the number of events as normal, high, or low. Notice how the font color and type automatically changes by resizing the gate.




Tokens to control page visibility

Use token values to control whether or not individual layout pages are shown or hidden from view. Create hidden pages for your add-on markers or reflex testing that will automatically become visible in your layout based upon a particular statistic or conditional criteria occurring during your analysis. For example, hide your ZAP 70 add-on page until your CLL patient data displays a population showing co-expression of CD5+/CD19+ cells greater than 20%. Design alternate report pages based upon the patient sample types. The possibilities are endless, yet defined and controlled by you and your data.

Using Tokens in Batch Processing

We have used tokens to export statistics and keywords to Excel Spreadsheets, text file elements, or other report format options as part of our Batch Processing Actions for many years now. Now you can use tokens to control which actions are active or not during the batch as well. As an example, let's say that you normally want to export a jpeg image of your SS vs CD45 plot. But on occasion you would like to send extra jpegs of other plots to be included with your reports. You can use your custom conditional tokens to define when a certain plot should be included or not.