What’s New in FCS Express 7 IVD for Clinical and Validated Laboratories

Presented by:

Holly A. Bonar, MS, SCYM(ASCP)CM

Senior Clinical Applications Scientist

De Novo Software/Dotmatics

Wednesday November 4, 2026 11:00 AM PDT / 2:00 PM EDT

FCS Express 7 IVD 7.32.0070 is here with new enhancements designed to make clinical and validated workflows more efficient!  This webinar is specifically for clinical diagnostic laboratories and anyone working in a GxP/GMP validated environment.

We will discuss new features including:

• Dynamic Markers: a new automatic peak-finding tool for histograms
• Improvements to security and logging features, including new functionality with electronic signatures
• New/Updated Instrument Specific Settings (ISS) for the BD FACSDiscover A8/S8, Beckman Coulter CytoFLEX / DxFLEX, and Cytek Aurora-Evo
• New and improved statistical and QC reporting capabilities for compensation matrices and data file-derived statistics grids
• Performance improvements designed to help speed up layouts

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***Continuing Education Opportunity***

From Design to Data: Building and Validating a 23-Color Spectral B-NHL Panel

Presented by:

Jessica Hughes, MS, MLS, SCYM(ASCP)CM

Staff Scientist

City of Hope Hospital, San Diego, CA

Thursday November 5, 2026 11:00 AM PDT / 2:00 PM EDT

This webinar presents the end-to-end development and validation of a 23-color spectral flow cytometry panel for B-cell non-Hodgkin lymphoma (B-NHL). Attendees will gain an inside look at the panel design process, including fluorophore selection, marker prioritization, and the trial-and-error optimization required to balance resolution, spreading error, and biological relevance. The session will detail the analytical validation of the panel — covering accuracy, precision, sensitivity, and specificity — and demonstrate how these metrics were established using real experimental data. We will also introduce a custom analysis template that  incorporates the high-dimensional tools UMAP and FlowSOM, showing how these approaches enhance population discovery and improve workflow in complex hematopathology panels.

Objectives:

• Identify the criteria used to select fluorochromes and prioritize markers when designing a 23-color spectral B-NHL panel.
• List the four analytical validation parameters: accuracy, precision, sensitivity, and specificity, and describe how each is measured to confirm clinical panel performance.
• Describe how UMAP and FlowSOM are used within a custom analysis template to identify and characterize cell populations in high-dimensional spectral flow cytometry data

Instruction Level: Advanced

Contact Hours: 1.0

Program #: 231-001-26

De Novo Software is approved as a provider of continuing education programs in the clinical laboratory sciences by the ASCLS P.A.C.E.® Program.

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